Mo Salah becomes Champions League's 10th-highest scorer of all time
Goals from Andy Robertson and Mohamed Salah had the Reds 2-0 up inside six minutes of the league-phase opener at Anfield on Wednesday.
Marcos Llorente's double levelled proceedings but Virgil van Dijk headed in a 92nd-minute winner to clinch the points on matchday one.
All Red Video members can view a recap and the entire 90 minutes below.
The Dutch midfielder impressed yet again as the Reds kicked off their Champions League campaign with a dramatic 3-2 victory at Anfield on Wednesday night.
Isak was making his first Liverpool appearance since his £130million move from Newcastle.
And as Liverpool stormed 2-0 ahead, he must have felt going on strike in his efforts to swap Tyneside for Merseyside was worth it.
The striker is at the heart of a £426million remodel that threatens to sweep through Europe.
Slot, celebrating his 47th birthday last night, won the Premier League title at a canter in his first season in charge despite spending just £10m on Federico Chiesa.
The only one on the pitch was in an Atletico Madrid shirt in the shape of Conor Gallagher.
The first goal arrived after three minutes, 32 seconds.
Salah fired a low cross into the visitors’ box and Robertson reacted with a flick that deflected off Pablo Barrios to give the Scot his first European strike in six years.
Anfield’s Egyptian King doubled the lead 120 seconds later.
There was true majesty about his strike, too, as he cut in with a trademark swerve before depositing his shot beyond Jan Oblak.
Liverpool would have been granted a ridiculous penalty had VAR not alerted referee Maurizio Mariani that he had just made a fool of himself.
He adjudged that Clement Lenglet had fouled Frimpong in the 35th minute but there was nothing in it.
Simeone’s side cut the deficit three minutes into first-half injury time.
Llorente was not picked up as he moved forward and poked the ball home.
Suddenly, the vibrant mood inside Anfield fell flat.
Isak lasted 58 minutes before being replaced by Ekitike, while Conor Bradley and Alexis Mac Allister took over from Frimpong and Cody Gakpo.
Slot’s attempt at firing things up should have worked, too but Salah somehow hit Dominik Szoboszlai’s perfect lay-off against the post.
The Reds appeared to pay the price when Llorente volleyed home his second nine minutes from time.
But skipper Van Dijk had the last say before Simeone got himself tangled in a ruck with the crowd near the dugout — and was red-carded.